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KMID : 0939920120440010069
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2012 Volume.44 No. 1 p.69 ~ p.72
A Case of Non-Hodgkin¡¯s Lymphoma in Patient with Coombs¡¯ Negative Hemolytic Anemia and Idiopathic Thrombocytopenic Purpura
Park So-Yeon

Kim So-Yon
Kim Eun-Sil
Choi Soon-Uk
Hyun Hee-Jae
Ahn Ju-Young
Lee Ju-Hyoung
Ryu Seo-Hee
Park Jae-Hyun
Lee Gyeong-In
Lee Hyo-Jin
Abstract
Coombs¡¯ negative autoimmune hemolytic anemia (AIHA) is a rare disease which shares similar clinical and hematological features with Coombs¡¯ positive AIHA, but its exact frequency remains unknown. There have been few reports of idiopathic thrombocytopenic purpura (ITP) and Coombs¡¯ negative AIHA associated with other lymphoproliferative disorders (LPDs). Since there is a well known association between LPDs and autoimmune phenomena, it is important to investigate the possibility of an underlying malignancy. We report a case of ITP and Coombs¡¯ negative AIHA associated with diffuse large B-cell lymphoma.
KEYWORD
Lymphoma, Hemolytic anemia, Coombs¡¯ test, Idiopathic thrombocytopenic purpura
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